Nicotinamide (>100 mg/day): Flushing of the face, arms & chest. Fe (doses of elemental Fe >120 mg/day): GI effects eg, nausea, vomiting, bloating & upper abdominal discomfort. Ginseng (high doses >3 g/day): HTN, nervousness, insomnia, edema, diarrhea & skin reactions. Royal jelly: Hypersensitivity reactions eg, eczema, rhinitis, urticaria & bronchospasm.